When you know and really understand that a great part of My character is longsuffering, you will never give up praying for those you know who need to come into My kingdom and also for those who have temporarily turned away from walking in My Spirit.
Keep praying, keep pursuing My Word, keep praising Me for hearing and answering your prayers. I did not give up on My servant Paul even when He continued to persecute Me. It was the prayer of Stephen and the rest of My friends who continually blessed their enemies that opened the door in the spirit realm for Me to bless Paul.
Your prayers are effectual. Ask My Holy Spirit to pray through you the prayers that need to be prayed and then begin to praise Me for hearing and answering your petitions. The phrase, "Give up," comes from the enemy, not Me. Never give up praying.
EXODUS 34:6; PSALM 86:15; ACTS 7:60